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The meglitinide drugs, starlix and prandin, have a much shorter duration of action.

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If you skip a meal, do not take your dose of prandin.

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The starting dose and dose adjustments for prandin combination therapy is the same as for prandin monotherapy.

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Simvastatin co-administration of 20 mg simvastatin and a single dose of 2 mg prandin after 4 days of once daily simvastatin 20 mg and three times daily prandin 2 mg resulted in a 26 increase in repaglinide cmax from 23.

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Rifampin co-administration of 600 mg rifampin and a single dose of 4 mg prandin after 6 days of once daily rifampin 600 mg resulted in a 32 and 26 decrease in repaglinide auc and cmax, respectively.

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